|
Partnering Events:
|
 |
|
|
Merck Innovation Symposium: siRNA Delivery
Corporate Needs Symposium Sponsor
Symposium Sessions |
| | Monday June 2 |
| | Tuesday June 3 |
| | Merck Innovation Symposium: siRNA Delivery |
| 3:30 | Merck Innovation Symposium: siRNA Delivery |
| 6:30 | Merck Innovation Symposium Reception |
| | Wednesday June 4 |
| | Thursday June 5 |
| |
Symposium Program |
| | Tuesday June 3 |
| Back to Top |
|
Merck Innovation Symposium: siRNA Delivery | Exhibit Hall C |
| - |
Labile Catalytic Packaging and Delivering of Short Interference RNA to Cancer Cells: Control of Gold Nanoparticles “out” of RNA Complexes
A.M. Chen, O. Taratula, D. Wei, T. Minko, H. He, Rutgers, The State of New Jersey, US |
| - |
In vitro transfection efficiency of chitosan nanoparticles for gene delivery
M. Malhotra, A. Kulamarva, S. Sebak, J. Bhathena, S. Prakash, McGill University, CA |
| - |
Toward in vivo Targeting Delivery of siRNA for Efficient Cancer Therapy
O. Taratula, P. Kirkpatrick, R. Salva, I. Pandya, T. Minko, H. He, Rutgers-Newark University, US |
| - |
SiRNA for Therapeutic Immuno-modulation: Simultaneous Delivery of Cytokine-targeted SiRNA and DNA Antigens to Dendritic Cells using Polymer Microcarriers
A. Singh, H. Nie, B. Ghosn, K. Roy, The University of Texas at Austin, US |
| - |
Multilayered ABCD Nanoparticles for siRNA delivery
M. Thanou, A. Miller, Imperial College London, UK |
| - |
Delivery systems for enhanced siRNA delivery
A-L. Bolcato-Bellemin, M-E. Bonnet, J-P. Behr, P. Erbacher, Polyplus-transfection, FR |
| Back to Top |
| 3:30 |
Merck Innovation Symposium: siRNA Delivery | Room 208 |
| 3:30 |
Introduction: siRNA Delivery
A. Sachs, Merck, US |
| 3:40 |
Development of a new RNAi therapeutics platform
J. Kamens, W. Salomon, H. Baigude, J. McCarroll, C.-S. Yang, P. Swain, T. Rana, T. Woolf, D. Samarsky, P. Pavco, RXi Pharmaceutical, US |
| 4:00 |
Amphoteric liposomes are a platform for multi-organ delivery of oligonucleotides
C. Reinsch, U. Rauchhaus, S. Panzner, novosom AG, DE |
| 4:20 |
Oral Delivery of Map4K4 siRNA to Macrophages Inhibits TNF alpha Production and Protects against a LPS-Galactosamine Challenge in Mice
M. Aouadi, G. Tesz, E. Soto, M. Wang, S. Nicoloro, G. Ostroff, M. Czech, University of Massachusetts Medical School, US |
| 4:40 |
Systemic Delivery of Targeted, siRNA-Containing Nanoparticles for the Treatment of Solid Tumors: Concept to Clinic
J.D. Heidel, J.Y-C. Liu, R.K. Zeidan, Y. Liang, S. Rele, M.E. Davis, Calando Pharmaceuticals, US |
| 5:00 |
Targeting and Delivery of siRNA using Nanoparticles Fabricated via the PRINT Process
D.A. Canelas, X. Gao, S. Tian, P.A. Ropp, J.M. DeSimone, University of North Carolina at Chapel Hill, US |
| 5:20 |
Long-Circulating Micelle-like DNA-encapsulating Nanoparticles for Systemic Gene Delivery
Y.T. Ko, W.C.A. Kale, V.P. Torchilin, Northeastern University, US |
| 5:40 |
Efficient siRNA Delivery by Secondary and Tertiary Amine Modified Polysaccharides
B. Ghosn, A. Singh, K. Roy, The University of Texas at Austin, US |
| Back to Top |
| 6:30 |
Merck Innovation Symposium Reception | Room 208 |
| |
Background
This symposium will focus on enabling technologies that can be applied to the efficient delivery of siRNA in vivo which results in reduced levels of specific mRNAs/proteins. In addition, technologies useful for the accelerated development of siRNA containing therapeutics are relevant. Specific areas of interest include:
Topics & Application Areas
- Biodegradable delivery components with low levels of toxicity
- Delivery systems for multiple tissues
- Delivery approaches amenable to alternate routes of administration
- Enhanced siRNA delivery using molecular targeting strategies
- Improved siRNA intracellular trafficking, endosomal escape and RISC incorporation
- Advanced siRNA structures which improve in vivo potency, stability, duration of action, specificity and toxicity profiles
- Whole animal methods for efficiently evaluating biodistribution and gene silencing
- Analytical methods for the physical and chemical characterization of complex assemblies
- Other
Questions
For more information, please contact:
Reid J. Leonard, Ph.D.
Executive Director, Licensing & External Research
BMB 3-410, Merck Research Laboratories
33 Avenue Louis Pasteur
Boston, MA 02115
Phone: 617-992-2321
E-mail:
www.merck.com/licensing/
To become a Corporate Symposium Sponsor such as Merck, or to present a
Corporate Needs Presentation, please contact Jennifer Rocha at
|
